However, oral bioavailability is much lower than injectable, meaning the doses are higher (3 mg, 7 mg, and 14 mg tablets compared to the 0.25 to 2.4 mg injectable range)
Furin cleavage of PA results in its oligomerization at the cell surface into a pre-pore that facilitates membrane interactions with edema factor and lethal factor
Water, Glycereth-26, Methylpropanediol, Butylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Neopentyl Glycol Diheptanoate, Polyglyceryl-3 Methylglucose Distearate, PEG-240/HDI Copolymer Bis-Decyltetradeceth-20 Ether, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Glyceryl Stearate, Cyclopentasiloxane, PEG-60 Hydrogenated Castor Oil, Cyclohexasiloxane, Ammonium Acryloyldimethyltaurate/VP Copolymer, C12-16 Alcohols, Glutathione(990 ppm), Palmitic Acid, Hydrogenated Lecithin, Ethylhexylglycerin, Adenosine, Diospyros Kaki Fruit Extract, Chloramine T, Sodium Bicarbonate, Sodium Carbonate, Propanediol, Sodium Hyaluronate Crosspolymer (50 ppm), Prunella Vulgaris Extract, Fucus Vesiculosus Extract, Hydrolyzed Glycosaminoglycans(30 ppm), Glycine, Sodium Hyaluronate (15 ppm), Serine, Glutamic Acid, Potassium Laurate, Benzyl Glycol, Aspartic Acid, Leucine, BHT, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Hydrolyzed Hyaluronic Acid(2.5 ppm), Histidine, Methionine, Cysteine, Ectoin, Ceramide NP, Water(Carbonated Water), Panthenol, Glyceryl Glucoside, Xylitylglucoside, Anhydroxylitol, Xylitol, Hyaluronic Acid(0.05 ppm), Hydrolyzed Collagen, Polyglyceryl-10 Laurate, Polyglyceryl-10 Stearate, Raspberry Ketone, Pantolactone, Sodium Ascorbyl Phosphate, Tripeptide-1, Hexapeptide-9, Acetyl Tetrapeptide-5, Copper Tripeptide-1, Biotin, Acetyl Tetrapeptide-2, Palmitoyl Pentapeptide-4, Hexapeptide-11, Pyridoxine, Folic Acid, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Tocopherol, Cyanocobalamin, Alanine/ Histidine/ Lysine Polypeptide Copper HCl, Tripeptide-32, Linoleic Acid, Riboflavin, Beta-Carotene, Inositol, Thiamine HCl, Disodium EDTA, Fragrance
References Institute NC, SEER Cancer Stat Facts
